Kristian Berg Selected Research

chlorin

9/2016	Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial.
3/2015	Studies of the photosensitizer disulfonated meso-tetraphenyl chlorin in an orthotopic rat bladder tumor model.
10/2011	Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization.

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Kristian Berg Research Topics

Disease

68	Neoplasms (Cancer) 04/2023 - 03/2002
13	Rupture 02/2020 - 03/2002
12	Glioma (Gliomas) 06/2022 - 04/2012
8	Breast Neoplasms (Breast Cancer) 01/2022 - 12/2006
8	Carcinoma (Carcinomatosis) 12/2017 - 04/2002
6	Adenocarcinoma 04/2023 - 10/2006
6	Sarcoma (Soft Tissue Sarcoma) 12/2017 - 12/2005
5	Necrosis 02/2020 - 05/2009
4	Glioblastoma (Glioblastoma Multiforme) 12/2022 - 07/2004
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2020 - 03/2013
3	Fibrosarcoma 09/2013 - 11/2006
2	Squamous Cell Carcinoma of Head and Neck 01/2020 - 06/2006
2	Leiomyosarcoma 12/2017 - 12/2017
2	Non-Muscle Invasive Bladder Neoplasms 11/2017 - 03/2015
2	Urinary Bladder Neoplasms (Bladder Cancer) 11/2017 - 03/2015
2	Prostatic Neoplasms (Prostate Cancer) 08/2014 - 07/2003
2	Colonic Neoplasms (Colon Cancer) 01/2014 - 01/2009
2	Photosensitivity Disorders (Photodermatitis) 04/2012 - 04/2005
2	Wounds and Injuries (Trauma) 10/2011 - 06/2009
2	Colorectal Neoplasms (Colorectal Cancer) 11/2006 - 06/2006
2	Infections 06/2006 - 05/2005
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2020
1	Brain Neoplasms (Brain Tumor) 01/2018
1	Hyperthermia 04/2016
1	Fibrosis (Cirrhosis) 01/2016
1	Fatty Liver 01/2016
1	Porphyrias (Porphyria) 01/2016
1	Carcinogenesis 01/2016
1	Ovarian Neoplasms (Ovarian Cancer) 05/2015

Drug/Important Bio-Agent (IBA)

32	Photosensitizing Agents (Photosensitizers)IBA 10/2021 - 03/2002
30	1-phenyl-3,3-dimethyltriazene (PDT)IBA 12/2022 - 01/2005
17	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 12/2005
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 06/2008
5	Immunotoxins (Immunotoxin)IBA 08/2015 - 03/2007
5	SaporinsIBA 09/2013 - 03/2006
4	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2022 - 12/2006
4	ProdrugsIBA 03/2021 - 07/2004
4	PorphyrinsIBA 04/2015 - 04/2005
4	di(4-sulfonatophenyl)diphenylporphineIBA 04/2012 - 06/2006
4	Proteins (Proteins, Gene)FDA Link 10/2011 - 03/2006
3	Fluorouracil (Carac)FDA LinkGeneric 03/2021 - 04/2016
3	Therapeutic UsesIBA 01/2020 - 05/2009
3	Cetuximab (Erbitux)FDA Link 01/2020 - 03/2007
3	ErbB Receptors (EGF Receptor)IBA 01/2020 - 03/2006
3	Cytosine DeaminaseIBA 01/2019 - 01/2014
3	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 12/2004
3	chlorinIBA 09/2016 - 10/2011
3	Gelonium multiflorum GEL proteinIBA 12/2013 - 03/2010
3	tetraphenylporphineIBA 04/2012 - 10/2006
2	CyclodextrinsIBA 04/2023 - 04/2015
2	protoporphyrin IXIBA 12/2022 - 12/2005
2	Biomarkers (Surrogate Marker)IBA 12/2022 - 11/2021
2	VaccinesIBA 06/2022 - 01/2018
2	Trastuzumab (Herceptin)FDA Link 11/2021 - 05/2015
2	EnzymesIBA 03/2021 - 12/2017
2	LipidsIBA 01/2020 - 04/2002
2	cercosporinIBA 01/2020 - 01/2019
2	phthalocyanineIBA 01/2020 - 06/2009
2	Caspase 3 (Caspase-3)IBA 01/2020 - 05/2015
2	Estrogen ReceptorsIBA 01/2019 - 01/2016
2	Flucytosine (Ancobon)FDA Link 01/2019 - 05/2014
2	Oxygen (Dioxygen)IBA 01/2018 - 07/2011
2	NanoconjugatesIBA 10/2017 - 04/2015
2	Tamoxifen FDA LinkGeneric 01/2016 - 04/2015
2	bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA 01/2014 - 04/2012
2	AluminumIBA 04/2012 - 06/2009
2	Epidermal Growth Factor (EGF)IBA 11/2006 - 03/2006
2	AcidsIBA 12/2005 - 04/2005
1	Liposomes (Liposome)IBA 04/2023
1	Immune Checkpoint InhibitorsIBA 01/2023
1	HMGB1 Protein (HMG1)IBA 06/2022
1	Ado-Trastuzumab EmtansineIBA 11/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 11/2021
1	pertuzumabIBA 11/2021
1	Sunitinib (Sutent)FDA Link 02/2020
1	Gemcitabine FDA Link 01/2020
1	IronIBA 01/2020
1	Silicon Dioxide (Silica)FDA LinkGeneric 11/2018
1	GoldIBA 11/2018
1	GalactosidasesIBA 12/2017
1	AntioxidantsIBA 12/2017
1	pheophorbide aIBA 11/2017
1	hypericinIBA 01/2017
1	mahuang-tangIBA 04/2016
1	Monoclonal AntibodiesIBA 08/2015
1	Tyrosine Kinase InhibitorsIBA 08/2015
1	Epithelial Cell Adhesion MoleculeIBA 08/2015
1	meso-tetraphenyl chlorin disulphonateIBA 07/2015
1	Temozolomide (Temodar)FDA LinkGeneric 07/2015
1	tetra(3-hydroxyphenyl)porphineIBA 04/2015

Therapy/Procedure

34	Therapeutics 01/2023 - 03/2002
27	Photochemotherapy (Photodynamic Therapy) 12/2022 - 03/2002
6	Drug Therapy (Chemotherapy) 01/2022 - 12/2005
2	Radiotherapy 08/2015 - 11/2009
1	Lasers (Laser) 01/2020
1	Oral Administration 01/2018
1	Semiconductor Lasers 12/2017
1	Intravesical Administration 11/2017
1	Catheters 11/2017
1	Molecular Targeted Therapy 08/2015